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Friday, 20 April 2018

Pharmaceutics book: Biosimulation in Drug Development Edited by Martin Bertau, Erik Mosekilde, and Hans V. Westerhoff

Subject: Pharmaceutics

Book Name: Biosimulation in Drug Development Edited by Martin Bertau, Erik Mosekilde, and Hans V. Westerhoff
Publication: Wiley
Page: 525


Content:
PART I INTRODUCTION
1 Simulation in Clinical Drug Development
2 Modeling of Complex Biomedical Systems
3 Biosimulation of Drug Metabolism
PART II SIMULATING CELLS AND TISSUES
4 Correlation Between In Vitro, In Situ, and In Vivo Models
5 Core-Box Modeling in the Biosimulation of Drug Action
6 The Glucose-Insulin Control System
7 Biological Rhythms in Mental Disorders
8 Energy Metabolism in Conformational Diseases
9 Heart Simulation, Arrhythmia, and the Actions of Drugs
PART III TECHNOLOGIES FOR SIMULATING DRUG ACTION AND EFFECT
10 Optimizing Temporal Patterns of Anticancer Drug Delivery by Simulations of a Cell Cycle Automaton
11 Probability of Exocytosis in Pancreatic ß-Cells: Dependence on Ca2+ Sensing Latency Times, Ca2+ Channel Kinetic Parameters, and Channel Clustering
12 Modeling Kidney Pressure and Flow Regulation
13 Toward a Computational Model of Deep Brain Stimulation in Parkinson's Disease
14 Constructing a Virtual Proteasome
PART IV APPLICATIONS OF BIOSIMULATION
15 Silicon Cell Models: Construction, Analysis, and Reduction
16 Building Virtual Human Populations: Assessing the Propagation of Genetic Variability in Drug Metabolism to Pharmacokinetics and Pharmacodynamics
17 Biosimulation in Clinical Drug Development
18 Biosimulation and Its Contribution to the Three Rs

Click here to view the book